期刊
FOOD CHEMISTRY
卷 234, 期 -, 页码 220-229出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2017.04.177
关键词
Nanoliposome; Chitosan; Encapsulation; Rainbow trout skin peptide; Antioxidant maintenance
资金
- Iran Nanotechnology Initiative Council (INIC)
- Iran National Science Foundation (INSF) [95837482]
In this study, an antioxidant peptide fraction with a molecular mass <30 kDa (PF30) isolated from rainbow trout (Oncorhynchus mykiss) skin gelatin hydrolysates was encapsulated in chitosan-coated nanoliposomes. The mean particle size of liposomal nanovesicles containing PF30 was found to be in the range 163.4-234 nm with a low polydispersity index (PDI < 0.5); furthermore, the zeta-potential changed from +3.9 mV in uncoated liposomes to +45.5 mV in biopolymer-coated liposomes. FTIR spectra showed electrostatic interactions as well as hydrogen bonding between phospholipid head groups. and amine groups of chitosan. The entrapment efficiency of PF30 (2 mg/ml) was found to be highest in nanoliposomes coated with 0.4% (w/v) chitosan. Biopolymer-coated liposomes demonstrated more sustained peptide release behavior in vitro. Moreover, the chitosan-coated nanoliposomes maintained the antioxidant activity of the PF30 and could be considered a potential candidate for efficient delivery of bioactive compounds in nutraceutical and functional foods. (C) 2017 Elsevier Ltd. All rights reserved.
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