期刊
FOOD CHEMISTRY
卷 231, 期 -, 页码 42-50出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2017.03.121
关键词
Konjac glucomannan; Dispersibility; Degradation; gamma-Irradiation; Physicochemical properties; Antioxidation; LO2 cell
资金
- Natural Science Project of Xiamen Medical College [Z2013-05]
- Project for Outstanding Young Scientific Researcher from Fujian Higher College [ZA152711]
- Key Program of Natural Science for Yong Scholars from Fujian Higher College [JZ160495]
- National Natural Science Foundation of China [31471704, 31279817]
Konjac glucomannan (KGM) is an important functional polysaccharide in food research. However, unstable dispersibility of KGM inhibits its in-depth study and wide application. In this study, a degraded KGM (100 kGy-KGM), which showed excellent dispersibility and specific physicochemical properties, were obtained by gamma-irradiation in a dosage of 100 kGy. We investigated the protective effect of 100 kGy-KGM against H2O2 induced oxidative damage in LO2 cells. Our results demonstrated that pretreatment of LO2 cells with 100 kGy-KGM not only significantly increased cellular survivals and activities of GSH-Px and CAT, but also reduced levels of LDH, MDA and intracellular accumulation of ROS. The marked protective effect against oxidative damage and excellent dispersibility in 100 kGy-KGM allowed its possible use as an antioxidant. Our study provided fundamental knowledge to understand the structure-functions relationships of degraded-KGM, which could result in a theoretical guidance for the future application of KGM. (C) 2017 Elsevier Ltd. All rights reserved.
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