期刊
EMERGING INFECTIOUS DISEASES
卷 27, 期 5, 页码 1522-1524出版社
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2705.210191
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资金
- INOVA Fiocruz
- D'Or Institute for Research and Education
- Fundacao de Amparo a Pesquisa do Estado do Rio de Janeiro
- Serrapilheira Institute
The case of reinfection from distinct virus lineages in Brazil with the E484K mutation raises concerns about the duration of protective immune responses against SARS-CoV-2, especially with the variant associated with escape from neutralizing antibodies. This highlights potential challenges for virus control measures.
Uncertainty remains about how long the protective immune responses against severe acute respiratory syndrome coronavirus 2 persists, and suspected reinfection in recovered patients has been reported. We describe a case of reinfection from distinct virus lineages in Brazil harboring the E484K mutation, a variant associated with escape from neutralizing antibodies.
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