Recent advances in annulation reactions based on zwitterionic π-allyl palladium and propargyl palladium complexes

In the past few years, Pd-catalyzed annulation reactions through zwitterionic pi-allyl palladium intermediates have been extensively investigated. Meanwhile, zwitterionic pi-allyl palladium and propargyl palladium have also been successfully demonstrated to be a vital and versatile synthon for the construction of carbocyclic and heterocyclic compounds, which include both structural scaffolds used in the pharmaceutical industry and novel heterocyclic skeletons with potential biological appeal. This review highlights representative advances in organic synthesis based on zwitterionic pi-allyl palladium and propargyl palladium.

Automated summary

In recent years, Pd-catalyzed annulation reactions using zwitterionic pi-allyl palladium intermediates have been extensively studied, demonstrating their importance in the synthesis of carbocyclic and heterocyclic compounds with potential pharmaceutical and biological applications. This review highlights the significant advances in organic synthesis based on zwitterionic pi-allyl palladium and propargyl palladium.