Co-occurrence of aflatoxins and ochratoxin A in dried fruits in Iran: Dietary exposure risk assessment

In this study, the contamination levels of aflatoxins (AFs) and ochratoxin A (OTA) in 88 collected samples from Iran's market including dried mulberry, date, fig, and apricot were evaluated. The margin of exposure (MOE) was estimated to assess the risk of dietary intake of aflatoxin B-1 (AFB(1)) and OTA. The incidence of AFB(1) in dried mulberry, date, fig and apricot samples was 45.5, 40.9, 59.1, and 81.8%, respectively. Although the mean total AFs content in contaminated samples of date (2.61 mu g/kg), fig (3.43 mu g/kg) and apricot (2.91 mu g/kg) was lower than the maximum limit set in the European Union (EU) (4 mu g/kg), dried mulberry samples showed a higher contamination level (4.12 mu g/kg). The co-occurrence of OTA and AFs were noted in 4 (18.9%), 2 (9.1%), 4 (18.2%), and 10 (45.5%) in the dried mulberry, date, fig and apricot samples, respectively. Based on the calculated MOE, the dietary exposure to AFs through the consumption of dried fruit in Iran poses a potential risk to consumer health. OTA was detected in 45.45%, 22.72%, 45.45%, and 50% of mulberry, date, fig and apricot samples, respectively. However, OTA levels in all types of dried fruit were below recommended level in EU regulation (10 mu g/kg) and MOE > 10000, representing no toxicological concerns for consumers. (C) 2017 Elsevier Ltd. All rights reserved.