Controllable synthesis of two adenosine 5′-monophosphate nucleotide coordination polymers via pH regulation: crystal structure and chirality

Two types of Cu(ii)-AMP-4,4 '-bipy coordination polymers, {[Cu(AMP)(4,4 '-bipy)(H2O)(3)]center dot 5H(2)O}n (1) and {[Cu-2(HAMP)(2)(4,4 '-bipy)(2)(H2O)(4)]center dot 2NO(3)center dot 11H(2)O}n (2) (Na(2)AMP = adenosine 5 '-monophosphate disodium salt), were synthesised through pH control. X-ray single-crystal diffraction analysis revealed that 1 and 2 are one-dimensional (1D) coordinating coordination polymers. The nucleotide in 1 was not protonated whereas that in 2 was protonated. With the protonated NO3- in 2 entering the crystal lattice, it plays a role in balancing the charge. The chirality was studied using solid-state circular dichroism (CD) spectroscopy based on the analysis of crystal structures.

Automated summary

Through pH control, two types of Cu(ii)-AMP-4,4'-bipy coordination polymers were successfully synthesized and their structures were determined using X-ray single-crystal diffraction analysis. One nucleotide remained unprotonated while the other was protonated, with the protonated NO3- playing a role in charge balancing within the crystal lattice. The chirality of these compounds was studied using solid-state circular dichroism spectroscopy based on crystal structure analysis.