期刊
MATERIALS CHEMISTRY FRONTIERS
卷 5, 期 12, 页码 4368-4400出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0qm01099e
关键词
-
资金
- National Institutes of Health [1UG3TR003148-01, 5RC2DK118640]
- American Heart Association [18TPA34230036, 442611-NU-80922]
- 2232 International Fellowship for Outstanding Researchers Program of TuBTAK [118C346]
Hydrogels are essential biomaterials with applications in drug and cell delivery, tissue engineering, 3D printing, sensing, and actuating. The advent of self-healing hydrogels allows for smarter materials with sustainable mechanical properties under stress. The self-healing mechanisms of these materials rely on chemical bonding or physical interactions, but challenges in healing characteristics need to be addressed and investigated before clinical applications.
Hydrogels are important biomaterials that have several applications in drug and cell delivery, tissue engineering, three-dimensional (3D) printing and more recently, in sensing and actuating applications. With the advent of self-healing hydrogels, it is becoming possible to have smarter materials with sustainable mechanical properties under stress and also added functionalities. The mechanisms responsible for the self-healing behavior of these materials are related to their internal structure and processes triggered by damage they may sustain. These mechanisms rely on either chemical bonding or physical interactions of the structural components of hydrogels, or on both. Many self-healing hydrogels have been developed and tested in vitro and in animals. However, there are still challenges, especially with healing characteristics that need to be addressed and investigated in animal experiments before their clinical applications can be initiated, for which a multidisciplinary approach is required. In the current paper, various biomedical applications of self-healing hydrogels are discussed in detail, highlighting current challenges and future prospects.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据