Coinfection With Human Herpesvirus (HHV)-6B in Immunocompetent, Healthy Individuals With Chromosomally Integrated HHV-6A

Immunocompetent sisters with chromosomally integrated human herpesvirus 6A (HHV-6A) transiently excreted HHV-6B genome in their saliva. They did not have past histories of exanthema subitum but had antibodies against HHV-6A and HHV-6B. This suggests that endogenous HHV-6A may modify the clinical features of HHV-6B coinfection.

Automated summary

Two immunocompetent sisters with chromosomally integrated HHV-6A transiently excreted HHV-6B genome in their saliva. Despite not having a history of exanthema subitum, they had antibodies against HHV-6A and HHV-6B, suggesting that endogenous HHV-6A may modify the clinical features of HHV-6B coinfection.