Solid lipid nanoparticles for oral drug delivery

Solid lipid nanoparticles (SLNs) are an incredibly resourceful drug delivery platform because of its diverse determination and modifiable lipid materials are making the topic exceptionally captivated in the latest year. The network of the SLNs improves drug stability, maintaining a strategic distance from proteolytic debasement after organization, and releasing the drug in a controlled way, which additionally offer a few advantages over ordinary details, including great physical stability, spherical morphology, uniform size, positive zeta potentials, typical high cell penetration efficiency, core-shell pattern and excipients of GRAS status make the SLNs delivery system all the more promising.Subsequently this fresh methodology of solid lipid nanoparticles hold tremendous promise for reaching at the objective of controlled and site exact for both oral and parenteral drug delivery system. The aim of the article is to review the diverse instrumental techniques have been decorated and oral administration of SLNs is logistically reviewed. (C) 2019 Elsevier Ltd. All rights reserved.

Automated summary

Solid lipid nanoparticles (SLNs) are a versatile drug delivery platform with advantages such as good stability, uniform size, and high cell penetration efficiency, making them promising for controlled and site-specific drug delivery. Various instrumental techniques have been reviewed for the oral administration of SLNs.