Rhodium(iii)-catalyzed switchable C-H acylmethylation and annulation of 2,2′-bipyridine derivatives with sulfoxonium ylides

A novel protocol for Rh(iii)-catalyzed switchable C-H acylmethylation and annulation of 2,2 '-bipyridine derivatives with sulfoxonium ylides is reported. This protocol provides a facile approach to synthesize structurally diverse acylmethylated 2,2 '-bipyridine derivatives and acyl pyrido[2,3-a]indolizines with a broad range of functional group tolerance.

Automated summary

A novel protocol for Rh(iii)-catalyzed switchable C-H acylmethylation and annulation of 2,2 '-bipyridine derivatives with sulfoxonium ylides has been reported, providing a facile approach to synthesize structurally diverse acylmethylated 2,2 '-bipyridine derivatives and acyl pyrido[2,3-a]indolizines with a broad range of functional group tolerance.