Use of an Intracranial Drain as a Conduit for Treatment of an Intracranial Streptococcus intermedius Abscess

Brain abscesses are difficult to manage clinically and often result in a poor outcome. Although surgical and medical therapeutics have progressed, there are still challenges that make treating intracranial abscesses problematic. One of these treatment barriers is the poor penetration of intravenous antibiotics to the infection source through the blood-brain barrier. In this case report, we will discuss the use of a surgical drain as a conduit for direct antibiotic administration for a rare, recurrent Streptococcus intermedius infection. This technique allows us to bypass the blood-brain barrier while also reducing the systemic effects of antibiotics. When used in conjunction with craniotomy and resection, direct antibiotic administration via a surgical drain proved to be effective at treating our patient's abscess and preventing recurrence.

Automated summary

Brain abscesses are challenging to manage, with poor penetration of antibiotics through the blood-brain barrier being a major obstacle. Direct antibiotic administration via a surgical drain can effectively treat abscesses and prevent recurrence, bypassing the blood-brain barrier.