期刊
FITOTERAPIA
卷 122, 期 -, 页码 138-143出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2017.09.006
关键词
Morus alba; Moraceae; Isoprenylated phenolics; Albasins A-D; Protein tyrosine phosphatase 1B
资金
- National Natural Science Foundation of China [21372049, 81222045]
- Shanghai Commission of Science and Technology [14431905400]
- National Key Research and Development Program of China [2016YFC1305500]
Two new Diels-Alder adducts, albasins A and B (1 and 2), one new isoprenylated 2-arylbenzofuran, albasin C (3), one new isoprenylated flavone, albasin D (4), together with sixteen known phenolic compounds, were isolated from the root bark of Morus alba. Their structures were elucidated by extensive spectroscopic analysis, including NMR, MS, and ECD data. All the new compounds and most of the known ones showed significant inhibitory effects on PTP1B in vitro with IC50 values ranging from 0.57 to 7.49 mu M.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据