期刊
FITOTERAPIA
卷 122, 期 -, 页码 119-125出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.fitote.2017.09.004
关键词
Lydian chinense; Lignanamides; Antihyperlipidemic activity
资金
- National Natural Science Foundation of China [21602047]
- Key Projects for Science and Technology Research Henan Educational Committee [14B360003]
- Basic Science Foundation of Henan University of Chinese Medicine [2014KYYWF-QN09]
- General Programs for Science and Technology Development of Zhengzhou [131PPTGG417-2]
Seven new lignanamides, lyciumamides D-J (1-4 and 9-11), together with nine known analogues (5-8 and 12-16), were isolated from the root bark of Lycium chinense. The structures of the isolated compounds were elucidated on the basis of NMR spectroscopic and HRESIMS data. All isolated compounds were evaluated for antihyperlipidemic activities in HepG2 cells. The primary structure-activity relationships were discussed.
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