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FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts
Timothy B. C. London et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The human RecQ helicases, BLM and RECQ1, display distinct DNA substrate specificities
Venkateswarlu Popuri et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structural basis of DNA quadruplex recognition by an acridine drug
Nancy H. Campbell et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
A Novel Small Molecule That Alters Shelterin Integrity and Triggers a DNA-Damage Response at Telomeres
Raphael Rodriguez et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
The Schizosaccharomyces pombe Pfh1p DNA Helicase Is Essential for the Maintenance of Nuclear and Mitochondrial DNA
Stefan F. Pinter et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Well-tempered metadynamics: A smoothly converging and tunable free-energy method
Alessandro Barducci et al.
PHYSICAL REVIEW LETTERS (2008)
A hitchhiker's guide to G-quadruplex ligands
David Monchaud et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2008)
Processing of DNA Replication and Repair Intermediates by the Concerted Action of RecQ Helicases and Rad2 Structure-Specific Nucleases
Robert Brosh et al.
PROTEIN AND PEPTIDE LETTERS (2008)
Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action
Anne De Cian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mechanism of acridine-based telomerase inhibition and telomere shortening
Mekala Gunaratnam et al.
BIOCHEMICAL PHARMACOLOGY (2007)
The yeast Pif1p DNA helicase preferentially unwinds RNA-DNA substrates
Jean-Baptiste Boule et al.
NUCLEIC ACIDS RESEARCH (2007)
Fluorescence-based melting assays for studying quadruplex ligands
Anne De Cian et al.
METHODS (2007)
Sequence effects of single base loops in intramolecular quadruplex DNA
Phillip A. Rachwal et al.
FEBS LETTERS (2007)
A new anticoagulant-antidote pair: Control of thrombin activity by aptamers and porphyrins
Astrid Joachimi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Structural basis for binding of porphyrin to human telomeres
Gary N. Parkinson et al.
BIOCHEMISTRY (2007)
Highly efficient G-quadruplex recognition by bisquinolinium compounds
Anne De Cian et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Quadruplex DNA: sequence, topology and structure
Sarah Burge et al.
NUCLEIC ACIDS RESEARCH (2006)
Human replication protein a unfolds telomeric G-quadruplexes
Tonatiuh Romero Salas et al.
NUCLEIC ACIDS RESEARCH (2006)
The DNA repair helicases XPD and FancJ have essential iron-sulfur domains
Jana Rudolf et al.
MOLECULAR CELL (2006)
Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6-and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation
MJB Moore et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates
JP Vaughn et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates
PL Opresko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
O Levran et al.
NATURE GENETICS (2005)
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ
R Litman et al.
CANCER CELL (2005)
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J
M Levitus et al.
NATURE GENETICS (2005)
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro
AJ Zaug et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter
AT Phan et al.
NATURE CHEMICAL BIOLOGY (2005)
The HRDC domain of BLM is required for the dissolution of double Holliday junctions
L Wu et al.
EMBO JOURNAL (2005)
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function
AM Burger et al.
CANCER RESEARCH (2005)
Highly prevalent putative quadruplex sequence motifs in human DNA
AK Todd et al.
NUCLEIC ACIDS RESEARCH (2005)
Prevalence of quadruplexes in the human genome
JL Huppert et al.
NUCLEIC ACIDS RESEARCH (2005)
Regulation of murine telomere length by Rtel:: An essential gene encoding a helicase-like protein
H Ding et al.
CELL (2004)
Timeline - Happy Hollidays: 40th anniversary of the Holliday junction
YL Liu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
L Wu et al.
NATURE (2003)
Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat
E Gavathiotis et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The cationic porphyrin TMPyP4 destabilizes the tetraplex form of the fragile X syndrome expanded sequence d(CGG)n
P Weisman-Shomer et al.
NUCLEIC ACIDS RESEARCH (2003)
The stability of intramolecular DNA quadruplexes with extended loops forming inter- and intra-loop duplexes
A Risitano et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2003)
G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition
MD Huber et al.
NUCLEIC ACIDS RESEARCH (2002)
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
A Siddiqui-Jain et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA
I Cheung et al.
NATURE GENETICS (2002)
Schizosaccharomyces pombe pfh1+ encodes an essential 5′ to 3′ DNA helicase that is a member of the PIF1 subfamily of DNA helicases
JQ Zhou et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Inhibition of the Bloom's and Werner's syndrome helicases by G-quadruplex interacting ligands
JL Li et al.
BIOCHEMISTRY (2001)
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei
C Schaffitzel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
P Mohaghegh et al.
NUCLEIC ACIDS RESEARCH (2001)
Pot1, the putative telomere end-binding protein in fission yeast and humans
P Baumann et al.
SCIENCE (2001)
The xeroderma pigmentosum group D (XPD) gene: one gene, two functions, three diseases
AR Lehmann
GENES & DEVELOPMENT (2001)
Differential regulation of human RecQ family helicases in cell transformation and cell cycle
T Kawabe et al.
ONCOGENE (2000)
Inhibition of unwinding of G-quadruplex structures by Sgs1 helicase in the presence of N,N′-bis[2-(1-piperidino)ethyl]-3,4,9,10-perylenetetracarboxylic diimide, a G-quadruplex-interactive ligand
HY Han et al.
BIOCHEMISTRY (2000)
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity
RM Brosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The Bloom's syndrome gene product interacts with topoisomerase III
L Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster
C Bai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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