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Recent progress in fluorescent probes for bacteria

期刊

CHEMICAL SOCIETY REVIEWS
卷 50, 期 13, 页码 7725-7744

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/d0cs01340d

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资金

  1. National Natural Science Foundation of China [21676113, 21772054]
  2. Distinguished Young Scholar of Hubei Province [2018CFA079]
  3. 111 Project [B17019]
  4. Scholar support program of CCNU [0900-31101090002]
  5. Guangdong Key Laboratory of Radioactive and Rare Resource Utilization [2018B030322009]
  6. Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules (KLSAOFM2012), Hubei University, Wuhan, P. R. China
  7. excellent doctorial dissertation cultivation grant of CCNU from the college's basic research and operation of MOE [2019YBZZ029]
  8. National Creative Research Initiative programs of the National Research Foundation of Korea - Korean government [2012R1A3A2048814]

向作者/读者索取更多资源

Bacteria are closely related to food fermentation, antibiotics, and pollutant degradation, playing both essential and harmful roles in human life. Therefore, effective strategies for accurate monitoring of bacteria are urgently needed. Fluorescence imaging technology, especially the design of organic fluorescent probes, has shown great potential in the detection and imaging of bacteria, offering high specificity and sensitivity with minimal invasiveness.
Food fermentation, antibiotics, and pollutant degradation are closely related to bacteria. Bacteria play an irreplaceable role in life. However, some bacteria seriously threaten human health and cause large-scale infectious diseases. Therefore, there is a pressing need to develop strategies to accurately monitor bacteria. Technology based on molecular probes and fluorescence imaging is noninvasive, results in little damage, and has high specificity and sensitivity, so it has been widely applied in the detection of bacteria. In this review, we summarize the recent progress in bacterial detection using fluorescence. In particular, we generalize the mechanisms commonly used to design organic fluorescent probes for detecting and imaging bacteria. Moreover, a perspective regarding fluorescent probes for bacterial detection is discussed.

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