期刊
ORGANIC CHEMISTRY FRONTIERS
卷 8, 期 15, 页码 4237-4287出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d0qo01480j
关键词
-
资金
- Department of Pharmaceuticals (DoP), Ministry of Chemicals and Fertilizers. Govt. of India
Multi-component reactions (MCRs) are important in synthetic and medicinal chemistry, providing high yields, time efficiency, and eco-friendliness for generating new chemical entities. Recent developments in MCRs have led to various synthetic approaches and a broad spectrum of organic frameworks.
Multi-component reactions (MCRs) are considered to be an important methodological arsenal in synthetic and medicinal chemistry. These reactions have been strategically employed in various synthetic transformations where classical methods usually involve many steps with tedious procedures. The MCR approach provides high yields, atom-/step economy, reduced reaction time, is eco-friendly, and acts as an amenable tool for the generation of a library of new chemical entities (NCEs), especially in the drug discovery process. Extensive research has led to copious developments in the field of MCRs. The developments have emerged with different synthetic approaches, including C-H activation, coupling, and cycloaddition, and eventually, such an amalgamation has enabled access to a broad spectrum of organic frameworks. The present review summarizes recent advancements in MCRs and their mechanistic insights from the last triennium (2017-2020).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据