Convergent total synthesis of corallocin A

The first total synthesis of corallocin A is described herein. The Suzuki coupling reaction as a key step proceeded with high stereoselectivity and in good yield. Robust transformations, including Vilsmeier-Haack formylation and Wittig reaction, allowed for effective access to corallocin A.

Automated summary

The first total synthesis of corallocin A was achieved with high stereoselectivity and good yield using the Suzuki coupling reaction as a key step. Robust transformations including Vilsmeier-Haack formylation and Wittig reaction were utilized for effective access to corallocin A.