New Drugs and Interventional Strategies for the Management of Hypertension

Essential hypertension is an important cause of cardiovascular morbidity and mortality worldwide with significant clinical and economic implications. The field of antihypertensive treatment already numbers numerous agents and classes of drugs. However, patients are still developing uncontrolled hypertension. Hence there is a continuous need for novel agents with good tolerability. Advances in this field are focusing both on pharmacotherapy, with the developments in traditional and non-traditional targets, as well as interventional techniques such as renal denervation and baroreflex activation therapy. It is likely that future strategies may involve a tailored approach to the individual patient, with genetic modulation playing a key role.

Automated summary

Essential hypertension is a crucial factor in global cardiovascular diseases and mortality, highlighting the need for continuous research and development of novel agents with good tolerability to manage uncontrolled hypertension. Future strategies may involve personalized approaches and genetic modulation in the treatment of hypertension.