4.6 Article

MMP8 increases tongue carcinoma cell-cell adhesion and diminishes migration via cleavage of anti-adhesive FXYD5

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Summary: Researchers are currently focusing on developing more selective MMP inhibitors by targeting other domains of MMPs through specific small molecule inhibitors or monoclonal antibodies. In addition, they are exploring unbiased global approaches, such as proteomics and N-terminomics, to discover new MMP substrates.

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