Zeolitic Imidazolate Framework-90 Nanoparticles as Nanozymes to Mimic Organophosphorus Hydrolase

Nanozymes are catalytically active nanomaterials that can mimic the catalytic properties of natural enzymes. However, little research has focused on nanozymes for mimicking organophosphate hydrolase (OPH) activity. Herein, we report that the zeolitic imidazolate framework-90 (ZIF-90) nanoparticles synthesized by the self-assembly of imidazole and metal ions have an average size of about 800 nm. They can serve as a new nanozyme to mimic OPH, which can effectively hydrolyze organophosphorus methyl parathion. More importantly, the as-prepared ZIF-90 nanozyme shows higher stability and superior recyclability. Our work will bring new possibilities for design and development of other novel nanozymes based on metal-organic framework materials.

Automated summary

ZIF-90 nanozyme synthesized from self-assembly of imidazole and metal ions can effectively hydrolyze organophosphorus methyl parathion, showing higher stability and superior recyclability. This work opens up new possibilities for designing and developing other novel nanozymes based on metal-organic framework materials.