期刊
ANNALS OF MEDICINE
卷 53, 期 1, 页码 682-692出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/07853890.2021.1930137
关键词
Atrial fibrillation; Rate control strategy; Electrophysiology; arrhythmias
资金
- Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia [IFKSURP-000]
Atrial fibrillation (AF) is a major cardiac arrhythmia associated with higher risk of cardiovascular morbidity and mortality. Rate control is one of the strategies for managing AF, aiming to improve symptoms and quality of life, although its effectiveness in preventing disease progression and reducing symptoms in highly symptomatic patients is limited. Despite being widely used, there are still debates regarding the use of rate control as first line management for all patients with AF.
Atrial fibrillation (AF) is one of the main cardiac arrhythmias associated with higher risk of cardiovascular morbidity and mortality. AF can cause adverse symptoms and reduced quality of life. One of the strategies for the management of AF is rate control, which can modulate ventricle rate, alleviate adverse associated symptoms and improve the quality of life. As primary management of AF through rate control or rhythm is a topic under debate, the purpose of this review is to explore the rationale for the rate control approach in managing AF by considering the guidelines, recommendations and determinants for the choice of rate control drugs, including beta blockers, digoxin and non- dihydropyridine calcium channel blockers for patients with AF and other comorbidities and atrioventricular nodal ablation and pacing. Despite the limitations of rate control treatment, which may not be effective in preventing disease progression or in reducing symptoms in highly symptomatic patients, it is widely used for almost all patients with atrial fibrillation. Although rate control is one of the first line management of all patient with atrial fibrillation, several issues remain debateable.
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