相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Hypolipidaemia among patients with PMM2-CDG is associated with low circulating PCSK9 levels: a case report followed by observational and experimental studies
Michael Chong et al.
JOURNAL OF MEDICAL GENETICS (2020)
Analysis of Protein Folding, Transport, and Degradation in Living Cells by Radioactive Pulse Chase
Nicholas McCaul et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2019)
Endoplasmic reticulum quality control of LDLR variants associated with familial hypercholesterolemia
Praseetha Kizhakkedath et al.
FEBS OPEN BIO (2019)
FURIN Inhibition Reduces Vascular Remodeling and Atherosclerotic Lesion Progression in Mice
Gopala K. Yakala et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Influence of a Coronary Artery Disease-Associated Genetic Variant on FURIN Expression and Effect of Furin on Macrophage Behavior
Guojun Zhao et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2018)
PCSK9 From Basic Science Discoveries to Clinical Trials
Michael D. Shapiro et al.
CIRCULATION RESEARCH (2018)
Posttranslational modification of proprotein convertase subtilisin/kexin type 9 is differentially regulated in response to distinct cardiometabolic treatments as revealed by targeted proteomics
Marie-Soleil Gauthier et al.
JOURNAL OF CLINICAL LIPIDOLOGY (2018)
Panorama Public: A Public Repository for Quantitative Data Sets Processed in Skyline
Vagisha Sharma et al.
MOLECULAR & CELLULAR PROTEOMICS (2018)
Compartment-Specific Biosensors Reveal a Complementary Subcellular Distribution of Bioactive Furin and PC7
Pierpaolo Ginefra et al.
CELL REPORTS (2018)
Threshold Effects of Circulating Angiopoietin-Like 3 Levels on Plasma Lipoproteins
Sergio Fazio et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2017)
The Metabolic Syndrome, Inflammation, and Colorectal Cancer Risk: An Evaluation of Large Panels of Plasma Protein Markers Using Repeated, Prediagnostic Samples
Sophia Harlid et al.
MEDIATORS OF INFLAMMATION (2017)
PCSK9 Association With Lipoprotein(a)
Hagai Tavori et al.
CIRCULATION RESEARCH (2016)
Recent Trends in Cardiovascular Mortality in the United States and Public Health Goals
Stephen Sidney et al.
JAMA CARDIOLOGY (2016)
Diagnostic utility of BNP, corin and furin as biomarkers for cardiovascular complications in type 2 diabetes mellitus patients
Shadia A. Fathy et al.
BIOMARKERS (2015)
Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
Jennifer G. Robinson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events
Marc S. Sabatine et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
The Plasma Level of Proprotein Convertase FURIN in Patients with Suspected Infection in the Emergency Room: A Prospective Cohort Study
N. Ranta et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2015)
Association of FURIN and ZPR1 polymorphisms with metabolic syndrome
Chikara Ueyama et al.
BIOMEDICAL REPORTS (2015)
The Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Active Site and Cleavage Sequence Differentially Regulate Protein Secretion from Proteolysis
John S. Chorba et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Isolation and characterization of the circulating truncated form of PCSK9
Bomie Han et al.
JOURNAL OF LIPID RESEARCH (2014)
Loss of Plasma Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) After Lipoprotein Apheresis
Hagai Tavori et al.
CIRCULATION RESEARCH (2013)
Brown and Goldstein: The Cholesterol Chronicles
Prashant Nair
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Furin-cleaved Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Is Active and Modulates Low Density Lipoprotein Receptor and Serum Cholesterol Levels
Michael T. Lipari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A novel split kinesin assay identifies motor proteins that interact with distinct vesicle populations
Brian Jenkins et al.
JOURNAL OF CELL BIOLOGY (2012)
Propeptides Are Sufficient to Regulate Organelle-Specific pH-Dependent Activation of Furin and Proprotein Convertase 1/3
Stephanie L. Dillon et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
In Vivo Evidence That Furin from Hepatocytes Inactivates PCSK9
Rachid Essalmani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel Domain Interaction Regulates Secretion of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Protein
Fen Du et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel therapeutic concepts - The epidemic of cardiovascular disease in the developing world: global implications
Bernard J. Gersh et al.
EUROPEAN HEART JOURNAL (2010)
Effects of the Prosegment and pH on the Activity of PCSK9 EVIDENCE FOR ADDITIONAL PROCESSING EVENTS
Suzanne Benjannet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation EVIDENCE FOR AN INTRACELLULAR ROUTE
Steve Poirier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
PCSK9: a convertase that coordinates LDL catabolism
Jay D. Horton et al.
JOURNAL OF LIPID RESEARCH (2009)
Self-association of human PCSK9 correlates with its LDLR-degrading activity
Daping Fan et al.
BIOCHEMISTRY (2008)
PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans
Thilina Dewpura et al.
FEBS JOURNAL (2008)
Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells
Markey C. McNutt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice
Thomas A. Lagace et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A-Functional consequences of natural mutations and post-translational modifications
Suzanne Benjannet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
JC Cohen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment
KN Maxwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver
SW Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
NARC-1/PCSK9 and its natural mutants -: Zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol
S Benjannet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype
KN Maxwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
M Abifadel et al.
NATURE GENETICS (2003)
Furin at the cutting edge: From protein traffic to embryogenesis and disease
G Thomas
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Ectodomain shedding of furin:: kinetics and role of the cysteine-rich region
JB Denault et al.
FEBS LETTERS (2002)
Analysis of connexin intracellular transport and assembly
JK VanSlyke et al.
METHODS-A COMPANION TO METHODS IN ENZYMOLOGY (2000)
分享论文
