期刊
MOLECULAR SYNDROMOLOGY
卷 12, 期 4, 页码 202-218出版社
KARGER
DOI: 10.1159/000514437
关键词
Down syndrome; Intellectual disability; Language impairment; Mouse models; Neurodevelopmental disorders; Alzheimer’ s disease; Biomarkers; Trisomy 21 Research Society
资金
- Center for Genomic Regulation (Barcelona, Spain)
- MRC [UKDRI-1014] Funding Source: UKRI
Research on Down syndrome has been increasing in recent years, with the Trisomy 21 Research Society being a leading scientific organization in this field. The Third International Conference of T21RS brought together scientists, families, and industry representatives to share discoveries on T21, including cognitive and behavioral challenges, comorbidities, and potential therapeutic approaches. This demonstrates a strong interest and ongoing advancement in understanding and treating conditions associated with T21.
Research focused on Down syndrome has increased in the last several years to advance understanding of the consequences of trisomy 21 (T21) on molecular and cellular processes and, ultimately, on individuals with Down syndrome. The Trisomy 21 Research Society (T21RS) is the premier scientific organization for researchers and clinicians studying Down syndrome. The Third International Conference of T21RS, held June 6-9, 2019, in Barcelona, Spain, brought together 429 scientists, families, and industry representatives to share the latest discoveries on underlying cellular and molecular mechanisms of T21, define cognitive and behavioral challenges and better understand comorbidities associated with Down syndrome, including Alzheimer's disease and leukemia. Presentation of cutting-edge results in neuroscience, neurology, model systems, psychology, cancer, biomarkers and molecular and phar-ma-cological therapeutic approaches demonstrate the compelling interest and continuing advancement in all aspects of understanding and ameliorating conditions associated with T21.
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