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Magnetically recoverable catalysts for the preparation of pyridine derivatives: an overview

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RSC ADVANCES
卷 11, 期 28, 页码 17456-17477

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ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ra02418c

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  1. Alzahra University
  2. MINECO [PID2019-109953GB-I00]
  3. RUDN University Strategic Academic Leadership Program

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Magnetically recoverable nano-catalysts have been widely used in chemical reactions, particularly in the synthesis of pyridine derivatives with multicomponent reactions, showcasing a range of excellent biological activities.
Magnetically recoverable nano-catalysts can be readily separated from the reaction medium using an external magnet. In recent years, chemistry researchers have employed them as catalysts in chemical reactions. The high surface area, simple preparation, and modification are among their major advantages. Pyridine derivatives are an important category of heterocyclic compounds, which show a wide range of excellent biological activities, including IKK-beta inhibitors, anti-microbial agents, A2A adenosine receptor antagonists, inhibitors of HIV-1 integrase, anti-tumor, anti-inflammatory, and anti-Parkinsonism. Recently, the catalytic activity of magnetic nanoparticles was investigated in multicomponent reactions in the synthesis of pyridine derivatives, which is discussed in this review.

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