Medical image analysis using wavelet transform and deep belief networks

This paper introduces a three-step framework for classifying multiclass radiography images. The first step utilizes a de-noising technique based on wavelet transform (WT) and the statistical Kolmogorov Smirnov (KS) test to remove noise and insignificant features of the images. An unsupervised deep belief network (DBN) is designed for learning the unlabelled features in the second step. Although small-scale DBNs have demonstrated significant potential, the computational cost of training the restricted Boltzmann machine is a major issue when scaling to large networks. Moreover, noise in radiography images can cause a significant corruption of information that hinders the performance of DBNs. The combination of WT and KS test in the first step helps improve performance of DBNs. Discriminative feature subsets obtained in the first two steps serve as inputs into classifiers in the third step for evaluations. Five frequently used classifiers including naive Bayes, radial basis function network, random forest, sequential minimal optimization, and support vector machine and four different case studies are implemented for experiments using the Image Retrieval in Medical Application data set. The experimental results show that the three-step framework has significantly reduced computational cost and yielded a great performance for multiclass radiography image classification. Along with effective applications in image processing in other fields published in the literature, deep learning network in this paper has again demonstrated its robustness in handling a complex set of medical images. This implies that the proposed approach can be implemented in real practice for analysing noisy radiography images, which have many useful medical applications such as diagnosis of diseases related to lung, breast, musculoskeletal or pediatric studies. (C) 2017 Elsevier Ltd. All rights reserved.