4.7 Article

Longevity of Middle East Respiratory Syndrome Coronavirus Antibody Responses in Humans, Saudi Arabia

期刊

EMERGING INFECTIOUS DISEASES
卷 27, 期 5, 页码 1472-1476

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CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2705.204056

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资金

  1. National Institutes of Health, USA [PO1 AI060699]
  2. National Science and Technology Project [81772191]

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The study of antibody responses in MERS-CoV infection survivors in Saudi Arabia showed the presence of specific neutralizing antibodies up to 6 years postinfection. This finding provides crucial information for the development of MERS-CoV vaccines.
Understanding the immune response to Middle East respiratory syndrome coronavirus (MERS-CoV) is crucial for disease prevention and vaccine development. We studied the antibody responses in 48 human MERS-CoV infection survivors who had variable disease severity in Saudi Arabia. MERS-CoV specific neutralizing antibodies were detected for 6 years postinfection.

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