期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 9, 期 35, 页码 7238-7245出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1tb00964h
关键词
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资金
- National Key R&D Program of China [2019YFA0709200]
- National Natural Science Foundation of China [21874067, 91859112]
- CAS Interdisciplinary Innovation Team [JCTD-2020-08]
- PAPD program
- Fundamental Research Funds for the Central Universities [14380145]
- Major R&D Projects of Jiangxi Province [20194ABC28009]
In this study, the multi-enzyme-mimicking activities of CeO2 were regulated by a wet-chemical method at different synthesis temperatures, showing distinct responses to different temperatures. The regulation was attributed to the comprehensive effect of the oxygen species, size, and self-restoring abilities of CeO2. High-performance CeO2 can be rationally designed by a specific synthesis temperature, and guidelines from radar chart analysis can promote the biomedical applications of ceria-based nanozymes.
Ceria (CeO2) nanozymes have drawn much attention in recent years due to their unique physiochemical properties and excellent biocompatibility. It is therefore very important to establish a simple and robust guideline to regulate CeO2 with desired multi-enzyme-mimicking activities that are ideal for practical bioapplications. In this work, the multi-enzyme-mimicking activities of CeO2 were regulated in a facile manner by a wet-chemical method with different synthesis temperatures. Interestingly, a distinct response in multi-enzyme-mimicking activities of CeO2 was observed towards different synthesis temperatures. And the regulation was ascribed to the comprehensive effect of the oxygen species, size, and self-restoring abilities of CeO2. This study demonstrates that high-performance CeO2 can be rationally designed by a specific synthesis temperature, and the guidelines from radar chart analysis established here can advance the biomedical applications of ceria-based nanozymes.
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