期刊
EPIDEMIOLOGY AND INFECTION
卷 149, 期 -, 页码 -出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S0950268821001333
关键词
COVID-19; herpes infections; immune system; psychoneuroimmunology; SARS-CoV-2
资金
- Seville University (Immunology area), Department of Medical Biochemistry, Molecular Biology and Immunology
- Ministry of Economy, Industry and Competitiveness (MINECO) [BFU2017-85832-R]
Some patients exhibit herpes virus infections during the COVID-19 pandemic, possibly influenced by the underlying SARS-CoV-2 infection. The study suggests that the COVID-19 pandemic can cause immunodeficiencies that increase the risk of other viral infections.
The appearance on the skin of herpes virus lesions, concomitantly with the coronavirus disease 2019 (COVID-19) pandemic, leads us to suspect an underlying infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Diagnostic reverse transcriptase polymerase chain reaction tests and immunoglobulin M (IgM) and IgG seroconversion studies have therefore been carried out. We present three cases of herpes virus infections in immunocompetent patients: one of the infections was herpes simplex 1 in a 40-year-old woman, and the other two were herpes varicella-zoster infections in a 62-year-old man and a 25-year-old woman. The patients were in the care of the southern health district of Seville of the SAS (Andalusian Health Service) during the Spanish state of alarm over the COVID-19 pandemic. The SARS-CoV-2 infection was confirmed in only one of the three cases. In this study, we briefly review the etiopathogenic role of the COVID-19 pandemic situation, whereby immunodeficiencies are generated that favour the appearance of other viral infections, such as herpes virus infections.
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