期刊
CURRENT OPINION IN BIOMEDICAL ENGINEERING
卷 17, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.cobme.2020.100248
关键词
Bone defect; Orthopedics; Tissue engineering; Injection molding; Electrospinning; 3D printing
资金
- NSF [CBET 1927628]
- UTEP
- Gates Millennium Scholarship Program
- NSF-MRI [DMR 1826268]
- National Institute of General Medical Sciences of the National Institutes of Health [RL5GM118969, TL4GM118971, UL1GM118970]
Bone tissue engineering aims to regenerate damaged or diseased bones using a combination of cells, growth factors, and biomaterials. Recent advances in the field have focused on the role of biomaterials as scaffolding materials, with studies exploring the use of bioceramics, composites, and various hydrogels, as well as their biocompatibility and structural efficacy.
Bone tissue engineering (BTE) aims to develop strategies to regenerate damaged or diseased bone using a combination of cells, growth factors, and biomaterials. This article highlights recent advances in BTE, with particular emphasis on the role of the biomaterials as scaffolding material to heal bone defects. Studies encompass the utilization of bioceramics, composites, and myriad hydrogels that have been fashioned by injection molding, electrospinning, and 3D bioprinting over recent years, with the aim to provide an insight into the progress of BTE along with a commentary on their scope and possibilities to aid future research. The biocompatibility and structural efficacy of some of these biomaterials are also discussed.
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