4.5 Review

Discovery methods of coagulation-inhibiting drugs

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Neutralization of EP217609, a new dual-action FIIa/FXa anticoagulant, by its specific antidote avidin: a phase I study

P. Gueret et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2017)

Article Hematology

Coagulation factor XI vaccination: an alternative strategy to prevent thrombosis

C. Zhong et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)

Article Cardiac & Cardiovascular Systems

Early non-persistence with dabigatran and rivaroxaban in patients with atrial fibrillation

Cynthia A. Jackevicius et al.

Article Chemistry, Medicinal

Structure-Based Design of Macrocyclic Factor XIa Inhibitors: Discovery of the Macrocyclic Amide Linker

James R. Corte et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Hematology

A kallikrein-targeting RNA aptamer inhibits the intrinsic pathway of coagulation and reduces bradykinin release

K. -A. Steen Burrell et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)

Review Hematology

Inorganic polyphosphate: a key modulator of inflammation

S. M. Hassanian et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)

Editorial Material Hematology

A new antithrombotic strategy: inhibition of the C-terminal active site of protein disulfide isomerase

L. Wang et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)

Review Hematology

Laboratory Assessment of Direct Oral Anticoagulants

Jonathan Douxfils et al.

SEMINARS IN THROMBOSIS AND HEMOSTASIS (2017)

Article Hematology

Generation and characterization of aptamers targeting factor XIa

R. S. Woodruff et al.

THROMBOSIS RESEARCH (2017)

Article Chemistry, Medicinal

Macrocyclic factor XIa inhibitors

Cailan Wang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Chemistry, Medicinal

Macrocyclic inhibitors of Factor XIa: Discovery of alkyl-substituted macrocyclic amide linkers with improved potency

James R. Corte et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Chemistry, Medicinal

Discovery of novel aminobenzisoxazole derivatives as orally available factor IXa inhibitors

Isao Sakurada et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Emergency Medicine

Idarucizumab for the Reversal of Dabigatran

Michael Gottlieb et al.

ANNALS OF EMERGENCY MEDICINE (2017)

Article Hematology

Discovery and characterization of an antibody directed against exosite I of thrombin

T. P. Baglin et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2016)

Article Pharmacology & Pharmacy

Inhibition of Protein Disulfide Isomerase in Thrombosis

Roelof H. Bekendam et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2016)

Article Cardiac & Cardiovascular Systems

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS

Paulus Kirchhof et al.

EUROPACE (2016)

Review Pharmacology & Pharmacy

The discovery of dabigatran etexilate for the treatment of venous thrombosis

Martin Feuring et al.

EXPERT OPINION ON DRUG DISCOVERY (2016)

Review Chemistry, Medicinal

Factor XIa inhibitors: A review of the patent literature

Rami A. Al-Horani et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2016)

Article Oncology

The Intrinsic Pathway of Coagulation as a Target for Antithrombotic Therapy

Allison P. Wheeler et al.

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2016)

Article Cardiac & Cardiovascular Systems

Trends in the Management and Outcomes of Acute Pulmonary Embolism Analysis From the RIETE Registry

David Jimenez et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Article Biochemistry & Molecular Biology

Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant

Erin E. Soule et al.

NUCLEIC ACID THERAPEUTICS (2016)

Article Cardiac & Cardiovascular Systems

Effectiveness and Safety of Dabigatran, Rivaroxaban, and Apixaban Versus Warfarin in Nonvalvular Atrial Fibrillation

Xiaoxi Yao et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Article Cardiac & Cardiovascular Systems

Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation

Xiaoxi Yao et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2016)

Review Hematology

Modulation of the Coagulation Cascade Using Aptamers

Rebecca S. Woodruff et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2015)

Article Chemistry, Medicinal

Development of a novel class of potent and selective FIXa inhibitors

Ting Zhang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)

Review Hematology

Direct-acting oral anticoagulants: pharmacology, indications, management, and future perspectives

Antonio Gomez-Outes et al.

EUROPEAN JOURNAL OF HAEMATOLOGY (2015)

Review Hematology

Factor XI and contact activation as targets for antithrombotic therapy

D. Gailani et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2015)

Article Cardiac & Cardiovascular Systems

In vitro, antithrombotic and bleeding time studies of BMS-654457, a small-molecule, reversible and direct inhibitor of factor XIa

Pancras C. Wong et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2015)

Article Medicine, General & Internal

Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis

Harry R. Bueller et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Chemistry, Medicinal

Allosteric Inhibition of Human Factor Xla: Discovery of Monosulfated Benzofurans as a Class of Promising Inhibitors

Malaika D. Argade et al.

JOURNAL OF MEDICINAL CHEMISTRY (2014)

Article Multidisciplinary Sciences

Peptide-Based Anti-PCSK9 Vaccines - An Approach for Long-Term LDLc Management

Gergana Galabova et al.

PLOS ONE (2014)

Article Cell Biology

Affinity-based design of a synthetic universal reversal agent for heparin anticoagulants

Rajesh A. Shenoi et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Hematology

Stroke in Dialysis and Chronic Kidney Disease

Albert Power

BLOOD PURIFICATION (2013)

Article Cardiac & Cardiovascular Systems

Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences

Rajiv Chowdhury et al.

EUROPEAN HEART JOURNAL (2013)

Article Hematology

Inhibiting the intrinsic pathway of coagulation with a factor XII-targeting RNA aptamer

R. S. Woodruff et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2013)

Review Immunology

Active immunotherapy for chronic diseases

Martin F. Bachmann et al.

VACCINE (2013)

Review Pharmacology & Pharmacy

The discovery of rivaroxaban: translating preclinical assessments into clinical practice

Dagmar Kubitza et al.

FRONTIERS IN PHARMACOLOGY (2013)

Review Hematology

Aptamer-based modulation of blood coagulation

G. Mayer et al.

HAMOSTASEOLOGIE (2011)

Article Cardiac & Cardiovascular Systems

Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor

Pancras C. Wong et al.

JOURNAL OF THROMBOSIS AND THROMBOLYSIS (2011)

Article Cardiac & Cardiovascular Systems

Edoxaban: pharmacological principles, preclinical and early-phase clinical testing

Ramon A. Partida et al.

FUTURE CARDIOLOGY (2011)

Review Pharmacology & Pharmacy

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

C. Frank Bennett et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)

Article Pharmacology & Pharmacy

Tolerability and Pharmacokinetics of TB-402 in Healthy Male Volunteers

Peter Verhamme et al.

CLINICAL THERAPEUTICS (2010)

Article Biochemistry & Molecular Biology

An Anticoagulant RNA Aptamer That Inhibits Proteinase-Cofactor Interactions within Prothrombinase

Sai K. Buddai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Hematology

Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics

Richard C. Becker et al.

THROMBOSIS AND HAEMOSTASIS (2010)

Letter Hematology

Platelet inorganic polyphosphate decreases in patients with delta storage pool disease

L. Hernandez-Ruiz et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2009)

Article Hematology

An overview of the structure and function of thrombin

Earl W. Davie et al.

SEMINARS IN THROMBOSIS AND HEMOSTASIS (2006)

Article Hematology

What is all that thrombin for?

KG Mann et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2003)

Article Multidisciplinary Sciences

RNA aptamers as reversible antagonists of coagulation factor IXa

CP Rusconi et al.

NATURE (2002)