期刊
SCIENCE OF ADVANCED MATERIALS
卷 13, 期 2, 页码 209-216出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/sam.2021.3863
关键词
Silver Nanoparticles; FTIR; TEM; Phormidium sp.; Staphylococcus aureus
资金
- Deanship of Scientific Research at King Khalid University [(1)-127/40]
The research focused on bio-synthesizing silver nanoparticles using Phormidium sp. extract, which showed potential as an eco-friendly, time-saving strategy with medicinal significance. The combination of extract with AgNPs proved to be effective against MRSA, highlighting the antimicrobial potential of the produced particles.
The use and manufacturing of silver nanoparticles (AgNPs) have recently received considerable attention in many fields. Methicillin resistant Staphylococcus aureus (MRSA) causes infectious diseases in humans. Therefore, the aim of this work was to bio-synthesize AgNPs using the cyanobacteria Phormidium sp. extract and to use this extract with AgNPs to kill MRSA. Extracellular bio-formation of AgNPs by Phormidium sp. was scrutinized at various pH points and temperatures. Then, characterization and assessment of the antimicrobial power of the produced particles were performed. Extract and extract+ AgNPs were screened using Fourier Transform Infra-Red (FT-IR) spectroscopy and electron microscopy. The manufacturing and fastness of AgNPs were monitored visually (by color change) and spectroscopically. FT-IR analysis uncovered the biomolecules in the extract that caused the reduction of silver ions, protected them from aggregation and supplied them with high stability. Results indicated that AgNPs are spheres of 9 nm diameter. AgNPs combined with the extract proved to be a powerful antibacterial factor against MRSA. Consequently, biosynthesis of silver nano-spheres using Phormidium sp. with high antagonistic potency against MRSA is considered as an eco-friendly, time-saving strategy and with potential medicinal significance.
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