期刊
NEUROLOGICAL RESEARCH AND PRACTICE
卷 3, 期 1, 页码 -出版社
SPRINGERNATURE
DOI: 10.1186/s42466-021-00135-y
关键词
COVID-19; SARS-CoV-2; Neurologic sequelae; Cognitive impairment; CSF antibodies
A female patient experienced long-lasting cognitive impairment and persistent cerebrospinal fluid anti-SARS-CoV-2 antibodies 6 months after mild COVID-19, emphasizing the importance of neuropsychological testing and cerebrospinal fluid investigation in patients with relatively mild acute disease phase.
Neurological long-term sequelae are increasingly considered an important challenge in the recent COVID-19 pandemic. However, most evidence for neurological symptoms after SARS-CoV-2 infection and central nervous system invasion of the virus stems from individuals severely affected in the acute phase of the disease. Here, we report long-lasting cognitive impairment along with persistent cerebrospinal fluid anti-SARS-CoV-2 antibodies in a female patient with unremarkable standard examination 6 months after mild COVID-19, supporting the implementation of neuropsychological testing and specific cerebrospinal fluid investigation also in patients with a relatively mild acute disease phase.
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