Severe Brain Damage in a Moderate Preterm Infant as Complication of Post-COVID-19 Response during Pregnancy

Current evidence from the COVID-19 pandemic suggests that neonatal SARS-coronavirus-2 infections usually have a mild course. Data on how maternal infection during pregnancy affects fetal development are scarce. We present the unique case of a moderate preterm infant with intracranial bleeding and periventricular leukomalacia as a potential consequence of post-COVID-19 hyperinflammation during pregnancy.

Automated summary

The current evidence suggests that neonatal SARS-coronavirus-2 infections tend to be mild, but data on the impact of maternal infection during pregnancy on fetal development are limited. We present a unique case of a moderately preterm infant with intracranial bleeding and periventricular leukomalacia potentially as a consequence of post-COVID-19 hyperinflammation during pregnancy.