Creation of Mo/Tc@C60 and Au@C60 and molecular-dynamics simulations

The formation of middle- and/or high-weight atom (Mo, Au)-incorporated fullerenes was investigated using radionuclides produced by nuclear reactions. From the trace radioactivities of Mo-99/Tc-99m or Au-194 after high-performance liquid chromatography, it was found that the formation of endohedral and/or heterofullerene fullerenes in Mo-99/Tc-99m and Au-194 atoms could occur by a recoil process following the nuclear reactions. Furthermore, the Tc-99m (and Au-194) atoms recoiled against beta-decay remained present inside these cages. To confirm the produced materials experimentally, ab initio molecular dynamics (MD) simulations based on an all-electron mixed-basis approach were performed. The possibility of the formation of endohedral fullerenes containing Mo/Tc and Au atoms is verified; here, the formation of heterofullerenes is excluded by MD simulations. These findings suggest that radionuclides stably encapsulated by fullerenes could potentially play a valuable role in diagnostic nuclear medicine.

Automated summary

Through nuclear reactions, the formation of middle- and/or high-weight atom-incorporated fullerenes was investigated. Experimental results showed that radionuclides can be stably encapsulated by fullerenes, potentially playing a valuable role in diagnostic nuclear medicine.