4.7 Article

Assessing the Association of Mitochondrial Function and Inflammasome Activation in Murine Macrophages Exposed to Select Mitotoxic Tri-Organotin Compounds

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Inflammasomes and adaptive immune responses

Katherine A. Deets et al.

Summary: Recent research highlights the complex relationship between inflammasomes and adaptive immunity, focusing on how inflammasome activation influences the release of cytokines and antigens, shaping or inhibiting adaptive immune responses. Different tissue or cellular contexts may alter the effects of inflammasome activation on adaptive immunity, contributing to beneficial or detrimental outcomes in infectious diseases, cancer, and autoimmunity. The discussion by Deets and Vance explores the impact of inflammasome activation on adaptive immunity.

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