4.8 Article

DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell & Tissue Engineering

Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

Xuyu Qian et al.

CELL STEM CELL (2020)

Article Biochemical Research Methods

Influence of multiple hypothesis testing on reproducibility in neuroimaging research: A simulation study and Python-based software

Tuomas Puolivali et al.

JOURNAL OF NEUROSCIENCE METHODS (2020)

Article Biochemistry & Molecular Biology

Dysregulation of BRD4 Function Underlies the Functional Abnormalities of MeCP2 Mutant Neurons

Yangfei Xiang et al.

MOLECULAR CELL (2020)

Article Multidisciplinary Sciences

Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly

Lu Wang et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Neuronal defects in a human cellular model of 22q11.2 deletion syndrome

Themasap A. Khan et al.

NATURE MEDICINE (2020)

Article Biotechnology & Applied Microbiology

Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells

Yuki Miura et al.

NATURE BIOTECHNOLOGY (2020)

Article Biochemistry & Molecular Biology

Human 3D cellular model of hypoxic brain injury of prematurity

Anca M. Pasca et al.

NATURE MEDICINE (2019)

Article Biochemistry & Molecular Biology

Comprehensive Integration of Single-Cell Data

Tim Stuart et al.

Article Biotechnology & Applied Microbiology

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Daehwan Kim et al.

NATURE BIOTECHNOLOGY (2019)

Editorial Material Multidisciplinary Sciences

Assembling human brain organoids

Sergiu P. Pasca

SCIENCE (2019)

Article Biotechnology & Applied Microbiology

Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression

Christoph Hafemeister et al.

GENOME BIOLOGY (2019)

Article Biotechnology & Applied Microbiology

Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics

Kelly Street et al.

BMC GENOMICS (2018)

Article Biochemical Research Methods

Generation of cerebral organoids from human pluripotent stem cells

Madeline A. Lancaster et al.

NATURE PROTOCOLS (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Multidisciplinary Sciences

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster et al.

NATURE (2013)

Article Biochemical Research Methods

Directed differentiation of forebrain GABA interneurons from human pluripotent stem cells

Yan Liu et al.

NATURE PROTOCOLS (2013)

Article Multidisciplinary Sciences

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

Taisuke Kadoshima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Deficits in human trisomy 21 iPSCs and neurons

Jason P. Weick et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

Bridget M. Dolan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors

Jie Lu et al.

HUMAN MOLECULAR GENETICS (2012)

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

Article Multidisciplinary Sciences

Spatio-temporal transcriptome of the human brain

Hyo Jung Kang et al.

NATURE (2011)

Article Neurosciences

Expression and significance of DSCAM in the cerebral cortex of APP transgenic mice

Yong-lin Jia et al.

NEUROSCIENCE LETTERS (2011)

Article Neurosciences

NMDA-Mediated Regulation of DSCAM Dendritic Local Translation Is Lost in a Mouse Model of Down's Syndrome

Alexandra Alves-Sampaio et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Developmental Biology

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

Anita Bhattacharyya et al.

DEVELOPMENTAL NEUROSCIENCE (2009)

Article Biochemistry & Molecular Biology

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

Jing Chen et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

The genetic architecture of Down syndrome phenotypes revealed by high-resolution analysis of human segmental trisomies

Jan O. Korbel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Pediatrics

Biometry of face and brain in fetuses with trisomy 21

AM Guihard-Costa et al.

PEDIATRIC RESEARCH (2006)

Article Biochemistry & Molecular Biology

Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome

K Amano et al.

HUMAN MOLECULAR GENETICS (2004)

Article Behavioral Sciences

Human neural stem cells: a new tool for studying cortical development in Down's syndrome

A Bhattacharyya et al.

GENES BRAIN AND BEHAVIOR (2003)