期刊
ANALYST
卷 146, 期 14, 页码 4446-4449出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1an00570g
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资金
- National Natural Science Foundation of China [U20A200458]
- Natural Science Foundation of Hebei Province [B2020201092]
- Foundation of the Department of Science and Technology of Hebei Province [19241303D]
- Priority Strategy Project of Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education [ts2019002]
The study explored the versatility of multicolor imaging of human tissues using staining with perylene monoimide-mannose conjugates PMI-Man and co-staining with PMI-Man and eosin. The results showed perfect histological morphology in confocal fluorescence microscopy and light microscopy, providing a universal colorful staining method for both cancer tissues and normal tissues.
The versatility of multicolor imaging of human tissues based on staining with perylene monoimide-mannose conjugates PMI-Man and co-staining with PMI-Man and eosin (P&E) was investigated for human cancer and normal tissues. Staining with PMI-Man or co-staining with PMI-Man and eosin showed a perfect histological morphology both in confocal fluorescence microscopy and light microscopy. This approach provided a universal colorful staining method for cancer tissues and normal tissues.
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