4.8 Article

Galenic Lab-on-a-Chip concept for lipid nanocapsules production

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Pharmacology & Pharmacy

Microfluidics for nanomedicines manufacturing: An affordable and low-cost 3D printing approach

Mattia Tiboni et al.

Summary: Innovative lab-on-a-chip technology microfluidics has become popular in the pharmaceutical field for producing nanomedicines in a scalable way. However, new users face barriers such as access to expensive equipment and fabrication expertise. 3D printing, particularly fused deposition modeling, offers a promising solution to overcoming these barriers and expanding the realm of microfluidics. By developing polypropylene-based microfluidic chips through this technology, affordable and effective production of nanomedicines can be achieved with tunable characteristics and efficient drug loading.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Article Chemistry, Multidisciplinary

Three-dimensional, symmetrically assembled microfluidic device for lipid nanoparticle production

Niko Kimura et al.

Summary: The study developed a three-dimensional symmetrically assembled microfluidic device named the 3D-iLiNP device with the aim of precise size control of large-sized LNPs. Through computational fluid dynamics simulation, the device was designed and demonstrated to improve the LNP size distribution. Results showed that LNPs with sizes between 90 and 120 nm exhibited higher gene silencing activity compared to other sizes. The 3D-iLiNP device is expected to enhance DDS performance by accurately controlling the size of LNPs.

RSC ADVANCES (2021)

Review Engineering, Chemical

Microfluidic Devices and 3D Printing for Synthesis and Screening of Drugs and Tissue Engineering

Harrson S. Santana et al.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2020)

Review Chemistry, Multidisciplinary

Nanocarriers for the Delivery of Medical, Veterinary, and Agricultural Active Ingredients

Paul L. Chariou et al.

ACS NANO (2020)

Article Pharmacology & Pharmacy

3D-printed microfluidic chip for the preparation of glycyrrhetinic acid-loaded ethanolic liposomes

Mattia Tiboni et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Review Chemistry, Multidisciplinary

Lipid nanocapsules to enhance drug bioavailability to the central nervous system

Rui Pedro Moura et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Pharmacology & Pharmacy

Molecular approaches for targeted drug delivery towards cancer: A concise review with respect to nanotechnology

Balak Das Kurmi et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2020)

Article Pharmacology & Pharmacy

Microfluidic manufacturing improves polydispersity of multicomponent polymeric nanoparticles

Kathrin Abstiens et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2019)

Review Engineering, Biomedical

Digital Manufacturing for Microfluidics

Arman Naderi et al.

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 21 (2019)

Review Biotechnology & Applied Microbiology

Nanopharmaceuticals and nanomedicines currently on the market: challenges and opportunities

Fatemeh Farjadian et al.

NANOMEDICINE (2019)

Review Pharmacology & Pharmacy

Nanocarrier-based systems for targeted and site specific therapeutic delivery

Joydeb Majumder et al.

ADVANCED DRUG DELIVERY REVIEWS (2019)

Review Pharmacology & Pharmacy

Advances in microfluidics for lipid nanoparticles and extracellular vesicles and applications in drug delivery systems

Masatoshi Maeki et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Review Pharmacology & Pharmacy

Current developments and applications of microfluidic technology toward clinical translation of nanomedicines

Dongfei Liu et al.

ADVANCED DRUG DELIVERY REVIEWS (2018)

Review Biochemistry & Molecular Biology

Translatable High Drug Loading Drug Delivery Systems Based on Biocompatible Polymer Nanocarriers

Weizhi Chen et al.

BIOMACROMOLECULES (2018)

Review Engineering, Chemical

A review on microreactors: Reactor fabrication, design, and cutting-edge applications

Prashant L. Suryawanshi et al.

CHEMICAL ENGINEERING SCIENCE (2018)

Article Chemistry, Analytical

3D Printing Solutions for Microfluidic Chip-To-World Connections

Sander van den Driesche et al.

MICROMACHINES (2018)

Article Biotechnology & Applied Microbiology

Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models

Chiara Bastiancich et al.

NANOMEDICINE (2018)

Review Chemistry, Multidisciplinary

Nanosystem trends in drug delivery using quality-by-design concept

Jing Li et al.

JOURNAL OF CONTROLLED RELEASE (2017)

Review Pharmacology & Pharmacy

Nanocarrier mediated combination drug delivery for chemotherapy - A review

R. Pushpalatha et al.

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY (2017)

Review Biochemical Research Methods

Passive and active droplet generation with microfluidics: a review

Pingan Zhu et al.

LAB ON A CHIP (2017)

Review Nanoscience & Nanotechnology

Quality-by-design of nanopharmaceuticals - a state of the art

Thierry Bastogne

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

Review Chemistry, Analytical

A Review on Micromixers

Gaozhe Cai et al.

MICROMACHINES (2017)

Article Engineering, Chemical

Multiphase microfluidic synthesis of micro- and nanostructures for pharmaceutical applications

Rui Ran et al.

CHEMICAL ENGINEERING SCIENCE (2017)

Review Pharmacology & Pharmacy

Lipid-based nanocarriers for oral peptide delivery

Zhigao Niu et al.

ADVANCED DRUG DELIVERY REVIEWS (2016)

Review Food Science & Technology

Formation of Food-Grade Nanoemulsions Using Low-Energy Preparation Methods: A Review of Available Methods

Jennifer S. Komaiko et al.

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY (2016)

Review Pharmacology & Pharmacy

Lipid-based nanoformulations for peptide delivery

Nada Matougui et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)

Review Pharmacology & Pharmacy

Microfluidics: a transformational tool for nanomedicine development and production

Shyam Garg et al.

JOURNAL OF DRUG TARGETING (2016)

Review Pharmacology & Pharmacy

Production of nanoparticle drug delivery systems with microfluidics tools

Ikram Ullah Khan et al.

EXPERT OPINION ON DRUG DELIVERY (2015)

Editorial Material Biotechnology & Applied Microbiology

Optimizing the discovery and clinical translation of nanoparticles: could microfluidics hold the key?

Jong-Min Lim et al.

NANOMEDICINE (2014)

Review Biochemical Research Methods

Microfluidic methods for forming liposomes

Dirk van Swaay et al.

LAB ON A CHIP (2013)

Review Chemistry, Physical

Nano-emulsions: Formation by low-energy methods

Conxita Solans et al.

CURRENT OPINION IN COLLOID & INTERFACE SCIENCE (2012)

Review Nanoscience & Nanotechnology

Microfluidic technologies for accelerating the clinical translation of nanoparticles

Pedro M. Valencia et al.

NATURE NANOTECHNOLOGY (2012)

Article Physics, Multidisciplinary

NANOTECHNOLOGY IN CANCER MEDICINE

Jennifer H. Grossman et al.

PHYSICS TODAY (2012)

Article Nanoscience & Nanotechnology

Nanostructuring polyetheretherketone for medical implants

Jasmin Althaus et al.

EUROPEAN JOURNAL OF NANOMEDICINE (2012)

Article Pharmacology & Pharmacy

Development and characterization of a novel lipid nanocapsule formulation of Sn38 for oral administration

Emilie Roger et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2011)

Review Biochemistry & Molecular Biology

Microfluidic Mixing: A Review

Chia-Yen Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2011)

Article Pharmacology & Pharmacy

Layer-by-layer surface modification of lipid nanocapsules

Samuli Hirsjaervi et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2010)

Article Pharmacology & Pharmacy

Interactions of lipid-based liquid crystalline nanoparticles with model and cell membranes

Justas Barauskas et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2010)

Article Chemistry, Physical

Nanoparticles from Lipid-Based Liquid Crystals: Emulsifier Influence on Morphology and Cytotoxicity

Sergio Murgia et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2010)

Article Pharmacology & Pharmacy

The adaptation of lipid nanocapsule formulations for blood administration in animals

J. Hureaux et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

Article Pharmacology & Pharmacy

The universality of low-energy nano-emulsification

Nicolas Anton et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

Review Pharmacology & Pharmacy

Lipid nanocapsules: A new platform for nanomedicine

N. T. Huynh et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2009)

Review Engineering, Chemical

Microfluidic-assisted synthesis of polymer particles

Christophe A. Serra et al.

CHEMICAL ENGINEERING & TECHNOLOGY (2008)

Review Biochemical Research Methods

Droplet microfluidics

Shia-Yen Teh et al.

LAB ON A CHIP (2008)

Article Instruments & Instrumentation

Miniaturized dynamic light scattering instrumentation for use in microfluidic applications

Thomas Q. Chastek et al.

REVIEW OF SCIENTIFIC INSTRUMENTS (2007)

Article Chemistry, Physical

Quantitative SAXS analysis of the P123/water/ethanol ternary phase diagram

S. S. Soni et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2006)

Review Engineering, Electrical & Electronic

Micromixers - a review

NT Nguyen et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2005)

Article Chemistry, Multidisciplinary

A microfluidic system for controlling reaction networks in time

H Song et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)

Article Chemistry, Multidisciplinary

A novel phase inversion-based process for the preparation of lipid nanocarriers

B Heurtault et al.

PHARMACEUTICAL RESEARCH (2002)