Transient receptor potential (TRP) channels in human colorectal cancer: evidence and perspectives

Colorectal cancer (CRC) is one of the leading causes of death in the civilized world. Transient receptor potential channels (TRPs) arc a heterogeneous family of cation channels that play an important role in gastrointestinal physiology. TRPs have been linked with carcinogenesis in the colon and their role as potential therapeutic targets and prognostic biomarkers is under investigation.

Automated summary

TRPs play a crucial role in the pathogenesis of colorectal cancer and could serve as potential therapeutic targets and prognostic biomarkers.