Mediating covalent crosslinking of single-chain nanoparticles through solvophobicity in organic solvents

We describe the photoinduced intrachain crosslinking of coumarin-containing copolymers in various organic solvents. Analysis of copolymer solvation and comparison to a molecular coumarin derivative revealed solvophobicity-driven crosslinking kinetics and chain compaction that facilitated the synthesis of single-chain nanoparticles.

Automated summary

This study demonstrates the photoinduced intrachain crosslinking of coumarin-containing copolymers in various organic solvents, with solvophobicity-driven crosslinking kinetics and chain compaction facilitating the synthesis of single-chain nanoparticles.