期刊
EUROPEAN POLYMER JOURNAL
卷 90, 期 -, 页码 37-53出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2017.03.002
关键词
Sterilization; Ionizing radiation; Polyurethane; Blooming; Macrophage; Oxidation
The surface state is a major parameter for the biocompatibility of medical devices. During storage, the blooming of additives may occur on the surface of polymers and modify their properties. In this study, the impact of sterilizing and oxidation treatments on blooming was studied. The study was realized on polyurethane used in the fabrication of catheters on which the blooming of antioxidant crystals has been previously observed. Sterilization by ionizing radiations (beta, gamma) was performed on this material and samples were submitted to different kinds of oxidation process (UV, H2O2 and macrophages action). Surface evolution was investigated using AFM microscopy, FTIR-ATR and SEM.
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