期刊
RSC ADVANCES
卷 11, 期 39, 页码 23922-23942出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/d1ra02764f
关键词
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资金
- Beijing Nova Program of Science and Technology [Z201100006820141]
- National Natural Science Foundation of China [22078346]
- Innovation Academy for Green Manufacture, CAS [IAGM2020C19]
- Henan Key Research and Development Project [202102210046]
- Hebei Natural Science Foundation [B2020103010]
- CAS Pioneer Hundred Program
Cadaverine shows great potential as an important monomer for high value-added products with promising market prospects. The most effective strategies for its synthesis involve green chemical and bioconversion technologies. This review focuses on the progress, strategies, and challenging issues of cadaverine synthesis, biosynthesis, and purification, highlighting both environmental and economic impacts.
Cadaverine has great potential to be used as an important monomer for the development of a series of high value-added products with market prospects. The most promising strategies for cadaverine synthesis involve using green chemical and bioconversion technologies. Herein, the review focuses on the progress and strategies towards the green chemical synthesis and biosynthesis of cadaverine. Specifically, we address the specific biosynthetic pathways of cadaverine from different substrates as well as extensively discussing the origination, structure and catalytic mechanism of the key lysine decarboxylases. The advanced strategies for process intensification, the separation and purification of cadaverine have been summarized. Furthermore, the challenging issues of the environmental, economic, and applicable impact for cadaverine production are also highlighted. This review concludes with the promising outlooks of state-of-the-art applications of cadaverine along with some insights toward their challenges and potential improvements.
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