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Emerging highly pathogenic avian influenza (H5N8) virus in migratory birds in Central China, 2020

期刊

EMERGING MICROBES & INFECTIONS
卷 10, 期 1, 页码 1503-1506

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/22221751.2021.1956372

关键词

HPAIV H5N8; phylogenetic analysis; migratory birds; histopathology; flyway

资金

  1. National Science and Technology Major Project [2018ZX10101004, 2020ZX10001016]
  2. National Forestry and Grassland Administration Project: Monitoring, Prevention and Control of African Swine Fever, Avian Influenza, and Other Key Wild Animal Diseases [2020076041]

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The study identified eleven highly pathogenic avian influenza H5N8 viruses that were detected in migratory birds in Central China between November and December 2020. These strains were found to be highly homologous to those isolated in Europe from October to December 2020, suggesting a possible spread from Siberia via migratory birds. The research also revealed that H5N8 virus infection in migratory birds could lead to severe pathological damage and high viral load in multiple organs.
Eleven highly pathogenic avian influenza H5N8 viruses (clade 2.3.4.4b) were detected in migratory birds in Central China between November and December 2020, which were highly homologous to strains isolated in Europe from October to December 2020. Phylogenetic analysis indicated that the strains in the study possibly spread from Siberia by migratory birds. In this study, we found H5N8 virus infection in migratory birds could cause severe pathological damage and high viral load in multiple organs.

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