Comparative Assessment of Antibacterial Efficacy of Commercially Available Different Dental Gels: An In-vitro Study

Background: The topical routes of administering drugs have certain visible advantages, such as the direct application of a drug to the site of action and persistence of action for a prolonged duration. More stability and better application property of gel allow its use for topical application. Objectives: To determine and compare antibacterial efficacy of commercially available different dental gels. Methods: For the evaluation of the antibacterial efficacy of commercially available different antiseptic gels on Streptococcus mutans and Lactobacillus acidophilus, well-diffusion method was used. To assess the antibacterial efficacy after incubation in an appropriate culture medium, diameter of zone of inhibition was measured. Results: Maximum zone of inhibition was found with Cure next gel (40 mm,40mm) followed by Hexigel (30 mm, 21mm), Mucopain (17 mm, 17mm), and Dologel (7 mm, 16mm) against S. mutans and L. acidophilus, respectively. Analysis of variance (ANOVA) and Post Hoc Test were used to analyze results statistically. The difference between commercially available different dental gels was statistically significant (P < 0.001) at a 5%. Conclusion: In the present study, it was observed that Curenext gel was more effective, followed by Hexigel, Mucopain gel, and Dologel on S. Mutans and L. Acidophilus.

Automated summary

This study evaluated and compared the antibacterial efficacy of different commercially available dental gels, with Curenext gel showing the highest zone of inhibition against Streptococcus mutans and Lactobacillus acidophilus. The statistical analysis indicated a significant difference between the various dental gels.