Breaking the symmetry: C1-salans with (N-H) backbones

We disclose a synthetic route that providess an unprecedented library of C-1 salan ligands endowed with (N-H) backbones, previously limited to N-methylated backbones. Efforts to identify a generic complexation protocol to yield the corresponding Cu(ii)-salan complexes demonstrate the scope and limitations of this approach.

Automated summary

A synthetic route has been revealed to create a diverse library of C-1 salan ligands with (N-H) backbones, extending beyond the previous limitations of N-methylated backbones. Efforts to find a generic complexation protocol for Cu(ii)-salan complexes have shown both the potential and constraints of this approach.