4.1 Article

Serum iron concentration is candidate inflammatory marker for respiratory diseases in beef cows

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JOURNAL OF VETERINARY MEDICAL SCIENCE
卷 83, 期 5, 页码 824-828

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JAPAN SOC VET SCI
DOI: 10.1292/jvms.21-0051

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beef cattle; haptoglobin; iron; respiratory disease; serum amyloid A

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Through a study of 20 Japanese Black cows, it was determined that serum iron concentration can be a satisfactory substitute for inflammatory markers such as haptoglobin and serum amyloid A in cows with respiratory diseases.
We hypothesized that the serum iron (Fe) concentration in cows with respiratory diseases is a satisfactory substitute for major inflammatory markers such as haptoglobin (HPT) and serum amyloid A (SAA). Twenty Japanese Black cows aged 279.6 +/- 120.0 days were enrolled, and divided into respiratory diseases and control groups based on the presence of clinical findings of respiratory diseases. As a result, area under the receiver operating characteristic curves for plasma HPT, SAA and serum Fe concentrations for respiratory disease-associated systemic inflammation were excellent, at 1.00, 0.96 and 0.97, respectively. Therefore we confirmed that the serum Fe concentration is a satisfactory substitute for HPT and SAA in beef cows with respiratory diseases.

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