Deep learning for COVID-19 chest CT (computed tomography) image analysis: A lesson from lung cancer

As a recent global health emergency, the quick and reliable diagnosis of COVID-19 is urgently needed. Thus, many artificial intelligence (AI)-base methods are proposed for COVID-19 chest CT (computed tomography) image analysis. However, there are very limited COVID-19 chest CT images publicly available to evaluate those deep neural networks. On the other hand, a huge amount of CT images from lung cancer are publicly available. To build a reliable deep learning model trained and tested with a larger scale dataset, the proposed model builds a public COVID-19 CT dataset, containing 1186 CT images synthesized from lung cancer CT images using CycleGAN. Additionally, various deep learning models are tested with synthesized or real chest CT images for COVID-19 and Non-COVID-19 classification. In comparison, all models achieve excellent results in accuracy, precision, recall and F1 score for both synthesized and real COVID-19 CT images, demonstrating the reliable of the synthesized dataset. The public dataset and deep learning models can facilitate the development of accurate and efficient diagnostic testing for COVID-19. (C) 2021 The Authors. Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.

Automated summary

To address the urgent need for COVID-19 diagnosis, AI-based methods for analyzing chest CT images have been proposed. By synthesizing a dataset and testing various deep learning models, accurate and efficient diagnostic testing for COVID-19 can be achieved.