期刊
KIDNEY360
卷 2, 期 8, 页码 1373-1379出版社
AMER SOC NEPHROLOGY
DOI: 10.34067/KID.0002962021
关键词
chronic kidney disease; arteriovenous fistula; dialysis; drug delivery; stenosis
资金
- Department of Health and Human Services (HHS), National Institutes of Health (NIH)
- National Heart, Lung, and Blood Institute [HL098967]
- HHS, NIH, National Institute of Diabetes and Digestive and Kidney Diseases [DK107870]
The hemodialysis population is growing, but challenges with vascular access persist. Issues like thrombosis and infection hinder long-term access and increase healthcare costs and patient morbidity. Recent innovations have been effective in addressing these problems.
The hemodialysis population continues to grow. Although procedures for dialysis have existed for >60 years, significant challenges with vascular access to support hemodialysis persist. Failure of arteriovenous fistulas (AVFs) to mature, loss of AVF and graft patency, thrombosis, and infection hinder long-term access, and add extra health care costs and patient morbidity. There have been numerous innovations over the last decade aimed at addressing the issues. In this study, we review the literature and summarize the recent evolution of drug delivery, graft development, minimally invasive AVF creation, and stem-cell therapy for hemodialysis access.
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