期刊
CUREUS JOURNAL OF MEDICAL SCIENCE
卷 13, 期 8, 页码 -出版社
SPRINGERNATURE
DOI: 10.7759/cureus.16913
关键词
corynebacterium bovis; cornea; microbial keratitis; corneal perforation; corneal infection
This report presents a rare case of severe corneal infection caused by Corynebacterium bovis on a background of viral keratitis, leading to corneal abscess formation and perforation.
We report a rare case of severe, non-contact lens-related Corynebacterium bovis corneal infection on a background of viral keratitis, resulting in corneal abscess formation with subsequent corneal perforation. An 89-year-old Caucasian lady presented with a significant epithelial defect and a dense stromal infiltrates on a background of herpes zoster keratitis, ultimately resulting in corneal perforation. Enrichment culture obtained from corneal scraping isolated the unusual organism Corynebacterium bovis. This was treated with a combination of culture-directed, targeted course of antibiotics and surgical interventions. To the best of our knowledge, this is the first reported case of profuse bacterial keratitis secondary to Corynebacterium bovis infiltration, on a background of viral keratitis, resulting in corneal abscess formation and subsequent perforation. This report highlights this rare bacterium's characteristics including its pathogenicity in causing severe corneal disease, particularly in immunosuppressed environments such as in this case, apparent antibiotic sensitivities & resistance, and potential transmission route.
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