期刊
DISEASES
卷 9, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/diseases9030046
关键词
COVID-19; vitamin C; acute kidney injury; oxidative stress; inflammatory cytokine storm
资金
- Department of Science and Technology of Henan Province [192102310570]
- Health Science and Technology Talents Overseas Training Project of Henan Province
The SARS-CoV-2 virus has caused the COVID-19 pandemic, leading to global public health crisis. High mortality rates are seen in elders and subjects with comorbidities. The cytokine storm feature of COVID-19 may cause damage to the kidneys.
The newly found SARS-CoV-2 has led to the pandemic of COVID-19, which has caused respiratory distress syndrome and even death worldwide. This has become a global public health crisis. Unfortunately, elders and subjects with comorbidities have high mortality rates. One main feature of COVID-19 is the cytokine storm, which can cause damage in cells and tissues including the kidneys. Here, we reviewed the current literature on renal impairments in patients with COVID-19 and analyzed the possible etiology and mechanisms. In addition, we investigated the potential use of vitamin C for the prevention of renal injury in those patients. It appears that vitamin C could be helpful to improve the outcomes of patients with COVID-19. Lastly, we discussed the possible protective effects of vitamin C on renal functions in COVID-19 patients with existing kidney conditions.
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